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What is a clinical trial?

Clinical trials enable researchers to try new treatments, tests, drugs, devices or procedures to support the prevention, detection, diagnoses or treatment of medical conditions and learn how to manage diseases. They require both ethical approval from a Human Research Ethics Committee (HREC) and governance authorisation to commence at any SA Health site.

There are two types of trials:

  1. interventional clinical trials assign participants to different treatment groups and compare outcomes
  2. observational clinical trials observe participants but do not influence their treatments, focusing instead on what happens in different environments.

Clinical trials for researchers

Find out more about clinical trial phases and clinical trial application submissions.

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Clinical trials for participants

Are you interested in being a research participant? Learn how clinical trials are conducted and approved.

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Research publications

Browse the latest CALHN research outcomes from a range of peer-reviewed sources.

This page was last updated 23 May 2025.

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